AbstractConnections play a vital role in the transfer of lateral forces and energy dissipation in cross-laminated timber (CLT) structural systems. However, moisture exposure (e.g., rain during or after construction) can affect the durability of CLT structural members and their connections due to the hygroscopic nature of wood. Limited knowledge exists on the moisture performance of CLT connections. Therefore, in this study, a CLT shear wall-to-diaphragm angle bracket connection was exposed to simulated rain and relative humidity cycling (wetting) and subsequent redrying followed by mechanical loading cyclic testing. Four wood species (Douglas-fir, southern pine, Norway spruce, and spruce-pine-fir) and three wetting durations were applied to understand the effect of moisture intrusion on the connection performance, which was evaluated in terms of strength, stiffness, and energy dissipation. Two force–displacement backbone models were fitted to the experimental data. The results suggest a statistically significant increase (9%–15% for different species) in the peak strength and no change in the stiffness and energy dissipation capacity after the wetting and redrying cycles. However, additional studies should be conducted to gain further insight into the observed increase in load-carrying capacity. Additionally, the authors caution against considering any strength increase until further studies are conducted.