Siegel, R. L., Miller, K. D. & Jemal, A. Cancer statistics, 2019. CA. Cancer J. Clin. 69, 7–34 (2019).
Etzioni, R. et al. The case for early detection. Nat. Rev. Cancer 3, 243–252 (2003).
Shapiro, S., Venet, W., Strax, P., Venet, L. & Roeser, R. Ten- to fourteen-year effect of screening on breast cancer mortality. J. Natl. Cancer Inst. 69, 349–355 (1982).
Tabár, L. et al. Reduction in mortality from breast cancer after mass screening with mammography. Randomised trial from the breast cancer screening working group of the Swedish National Board of Health and Welfare. Lancet (London, England) 1, 829–832 (1985).
Kolb, T. M., Lichy, J. & Newhouse, J. H. Comparison of the performance of screening mammography, physical examination, and breast US and evaluation of factors that influence them: an analysis of 27,825 patient evaluations. Radiology 225, 165–175 (2002).
Boyd, N. F. et al. Mammographic Density and the Risk and Detection of Breast Cancer. N. Engl. J. Med. 356, 227–236 (2007).
Pisano, E. D. et al. Diagnostic performance of digital versus film mammography for breast-cancer screening. N. Engl. J. Med. 353, 1773–1783 (2005).
Saslow, D. et al. American cancer society guidelines for breast screening with MRI as an adjunct to mammography. CA. Cancer J. Clin. 57, 75–89 (2007).
Lehman, C. D. et al. Cancer yield of mammography, MR, and US in high-risk women: prospective multi-institution breast cancer screening study. Radiology 244, 381–388 (2007).
Monticciolo, D. L. et al. Breast cancer screening in women at higher-than-average risk: recommendations from the ACR. J. Am. Coll. Radiol. 15, 408–414 (2018).
Stavros, A. T. et al. Solid breast nodules: use of sonography to distinguish between benign and malignant lesions. Radiology 196, 123–134 (1995).
Rahbar, G. et al. Benign versus malignant solid breast masses: US differentiation. Radiology 213, 889–894 (1999).
Kolb, T. M., Lichy, J. & Newhouse, J. H. Occult cancer in women with dense breasts: detection with screening US–diagnostic yield and tumor characteristics. Radiology 207, 191–199 (1998).
Gordon, P. B. & Goldenberg, S. L. Malignant breast masses detected only by ultrasound. A retrospective review. Cancer 76, 626–630 (1995).
Berg, W. A. & Gilbreath, P. L. Multicentric and multifocal cancer: whole-breast US in preoperative evaluation. Radiology 214, 59–66 (2000).
Kaplan, S. S. Clinical utility of bilateral whole-breast US in the evaluation of women with dense breast tissue. Radiology 221, 641–649 (2001).
Brem, R. F., Lenihan, M. J., Lieberman, J. & Torrente, J. Screening Breast ultrasound: past, present, and future. Am. J. Roentgenol. 204, 234–240 (2015).
Berg, W. A. et al. Combined screening with ultrasound and mammography vs mammography alone in women at elevated risk of breast cancer. JAMA J. Am. Med. Assoc. 299, 2151–2163 (2008).
Berg, W. A. et al. Ultrasound as the Primary Screening Test for Breast Cancer: Analysis From ACRIN 6666. J. Natl. Cancer Inst. 108, djv367 (2016).
Kaplan, S. S. Automated whole breast ultrasound. Radiol. Clin. N. Am. 52, 539–546 (2014).
Zanotel, M. et al. Automated breast ultrasound: basic principles and emerging clinical applications. Radiol. Med. 123, 1–12 (2018).
Samani, A., Zubovits, J. & Plewes, D. Elastic moduli of normal and pathological human breast tissues: an inversion-technique-based investigation of 169 samples. Phys. Med. Biol. 52, 1565–1576 (2007).
Sarvazyan, A. P. et al. Biophysical bases of elasticity imaging. Springer, Boston. 223–240. https://doi.org/10.1007/978-1-4615-1943-0_23 (1995).
Sewell, C. W. Pathology of benign and malignant breast disorders. Radiol. Clin. N. Am. 33, 1067–1080 (1995).
Sandrin, L. et al. Transient elastography: a new noninvasive method for assessment of hepatic fibrosis. Ultrasoun. Med. Biol. 29, 1705–1713 (2003).
Ophir, J., Céspedes, I., Ponnekanti, H., Yazdi, Y. & li, X. Elastography: A quantitative method for imaging the elasticity of biological tissues. Ultrason. Imaging 13, 111–134 (1991).
Doherty, J. R., Trahey, G. E., Nightingale, K. R. & Palmeri, M. L. Acoustic radiation force elasticity imaging in diagnostic ultrasound. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 60, 685–701 (2013).
Itoh, A. et al. Breast disease: clinical application of US elastography for diagnosis. Radiology 239, 341–350 (2006).
Sarvazyan, A. P., Rudenko, O. V., Swanson, S. D., Fowlkes, J. B. & Emelianov, S. Y. Shear wave elasticity imaging: A new ultrasonic technology of medical diagnostics. Ultrasound Med. Biol. 24, 1419–1435 (1998).
Nightingale, K. R., Palmeri, M. L., Nightingale, R. W. & Trahey, G. E. On the feasibility of remote palpation using acoustic radiation force. J. Acoust. Soc. Am. 110, 625–634 (2001).
Sharma, A. C., Soo, M. S., Trahey, G. E. & Nightingale, K. R. Acoustic radiation force impulse imaging of in vivo breast masses. IEEE Ultrason. Symp. 1, 728–731 (2004).
Nightingale, K., McAleavey, S. & Trahey, G. Shear-wave generation using acoustic radiation force: in vivo and ex vivo results. Ultrasound Med. Biol. 29, 1715–1723 (2003).
Bercoff, J., Tanter, M. & Fink, M. Supersonic shear imaging: a new technique for soft tissue elasticity mapping. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 51, 396–409 (2004).
Song, P. et al. Comb-push ultrasound shear elastography (CUSE): A novel method for two-dimensional shear elasticity imaging of soft tissues. IEEE Trans. Med. Imaging 31, 1821–1832 (2012).
Yoon, J. H., Jung, H. K., Lee, J. T. & Ko, K. H. Shear-wave elastography in the diagnosis of solid breast masses: What leads to false-negative or false-positive results?. Eur. Radiol. 23, 2432–2440 (2013).
Toprak, N., Yokus, A., Gündüz, M. & Akdenız, H. Histopathology and elastography discordance in evaluation of breast lesions with acoustic radiation force impulse elastography. Polish J. Radiol. 84, 224–233 (2019).
Fatemi, M. & Greenleaf, J. F. Ultrasound-stimulated vibro-acoustic spectrography. Science 280, 82–85 (1998).
Fatemi, M. & Greenleaf, J. F. Vibro-acoustography: An imaging modality based on ultrasound-stimulated acoustic emission. PNAS 96, 6603 (1999).
Kamimura, H. A. S. et al. Vibroacoustography for the assessment of total hip arthroplasty. Clinics 68, 463–468 (2013).
Kamimura, H. A. S., Urban, M. W., Carneiro, A. A. O., Fatemi, M. & Alizad, A. Vibro-acoustography beam formation with reconfigurable arrays. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 59, 1421–1431 (2012).
Konofagou, E. E. & Hynynen, K. Localized harmonic motion imaging: theory, simulations and experiments. Ultrasound Med. Biol. 29, 1405–1413 (2003).
Baggio, A. L., Kamimura, H. A. S., Henrique Lopes, J., Carneiro, A. A. O. & Silva, G. T. Parametric array signal in confocal vibro-acoustography. Appl. Acoust. 126, 143–148 (2017).
Maleke, C., Pernot, M. & Konofagou, E. E. Single-element focused ultrasound transducer method for harmonic motion imaging. Ultrason. Imaging 28, 144–158 (2006).
Payen, T. et al. Harmonic motion imaging of pancreatic tumor stiffness indicates disease state and treatment response. Clin. Cancer Res. 26, 1297–1308 (2020).
Han, Y., Wang, S., Payen, T. & Konofagou, E. Human breast tumor characterization on post-surgical mastectomy specimens using harmonic motion imaging (HMI). in IEEE International Ultrasonics Symposium, IUS (IEEE Computer Society, 2017). https://doi.org/10.1109/ULTSYM.2017.8091551
Chen, H. et al. Harmonic motion imaging for abdominal tumor detection and high-intensity focused ultrasound ablation monitoring: An in vivo feasibility study in a transgenic mouse model of pancreatic cancer. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 62, 1662–1673 (2015).
Vappou, J. et al. Non-contact, ultrasound-based indentation method for measuring elastic properties of biological tissues using Harmonic Motion Imaging (HMI). Phys. Med. Biol. 60, 2853–2868 (2015).
Han, Y., Wang, S., Hibshoosh, H., Taback, B. & Konofagou, E. Tumor characterization and treatment monitoring of postsurgical human breast specimens using harmonic motion imaging (HMI). Breast Cancer Res. 18, 46 (2016).
Han, Y. Development of a Harmonic Motion Imaging guided Focused Ultrasound system for breast tumor characterization and treatment monitoring. https://doi.org/10.7916/D8KS83H7 (2018).
Han, Y., Wang, S., Payen, T. & Konofagou, E. Fast lesion mapping during HIFU treatment using harmonic motion imaging guided focused ultrasound (HMIgFUS) in vitro and in vivo. Phys. Med. Biol. 62, 3111–3123 (2017).
Nakashima, K. & Moriya, T. Comprehensive ultrasound diagnosis for intraductal spread of primary breast cancer. Breast Cancer 20, 3–12 (2013).
Denis, M. et al. Comb-push ultrasound shear elastography of breast masses: initial results show promise. PLoS ONE 10, e0119398 (2015).
Shiina, T. et al. WFUMB guidelines and recommendations for clinical use of ultrasound elastography: part 1: basic principles and terminology. Ultrasound Med. Biol. 41, 1126–1147 (2015).
Chen, E. J., Adler, R. S., Carson, P. L., Jenkins, W. K. & O’Brien, W. D. Ultrasound tissue displacement imaging with application to breast cancer. Ultrasound Med. Biol. 21, 1153–1162 (1995).
Earl, H. Donegan WL, Spratt JS: Cancer of the breast 5th Edition. London, UK: Elsevier Science Ltd.; 2002. 1050pp. Breast Cancer Res. 6, 88 (2004).
Elseedawy, M., Whelehan, P., Vinnicombe, S., Thomson, K. & Evans, A. Factors influencing the stiffness of fibroadenomas at shear wave elastography. Clin. Radiol. 71, 92–95 (2016).
Samani, A. & Plewes, D. A method to measure the hyperelastic parameters of ex vivo breast tissue samples. Phys. Med. Biol. 49, 4395–4405 (2004).
Nabavizadeh, A. et al. Technical note: In vivo Young’s modulus mapping of pancreatic ductal adenocarcinoma during HIFU ablation using harmonic motion elastography (HME). Med. Phys. 45, 5244–5250 (2018).
Nabavizadeh, A. et al. Noninvasive Young’s modulus visualization of fibrosis progression and delineation of pancreatic ductal adenocarcinoma (PDAC) tumors using Harmonic Motion Elastography (HME) in vivo. Theranostics 10, 4614–4626 (2020).
Han, Y., Payen, T., Wang, S. & Konofagou, E. Focused ultrasound steering for harmonic motion imaging. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 65, 292–294 (2018).
Stavros, A. T., Rapp, C. L. & Parker, S. H. Breast ultrasound (Lippincott Williams & Wilkins, Philadelphia, 2004).
Barr, R. G. & Zhang, Z. Effects of Precompression on Elasticity Imaging of the Breast. J. Ultrasound Med. 31, 895–902 (2012).
Wade, O. L. Movements of the thoracic cage and diaphragm in respiration. J. Physiol. 124, 193–212 (1954).
Saharkhiz, N., Han, Y., Nabavizadeh, A., Ha, R. & Konofagou, E. A harmonic motion imaging (HMI) clinical system for detection and characterization of in vivo human breast masses – initial feasibility. In 2018 IEEE international ultrasonics symposium (IUS), Kobe, pp. 1–9. https://doi.org/10.1109/ULTSYM.2018.8579993 (2018).
Jianwen Luo, J. & Konofagou, E. E. A fast normalized cross-correlation calculation method for motion estimation. IEEE Trans. Ultrason. Ferroelectr. Freq. Control 57, 1347–1357 (2010).
Nightingale, K., Palmeri, M. & Trahey, G. Analysis of contrast in images generated with transient acoustic radiation force. Ultrasound Med. Biol. 32, 61–72 (2006).