AbstractMany countries and regions consider off-site construction a modern construction method that facilitates sustainability in the construction industry. Sustainability research in off-site construction (SROSC) is crucial for its development and is a nonnegligible part of its management. However, an in-depth understanding and critical analysis of SROSC to summarize recent research and inform future research directions are lacking. In this study, we address this issue by offering a mixed-review method integrating scientometric analysis and systematic review to explore state-of-the-art SROSC. We aim to uncover sustainability themes and topics, distinguish research trends, and identify gaps in knowledge that can be addressed in future research. Scientometric analysis was used to perform statistical analysis and visual map research on the knowledge landscape formed by 272 related studies of SROSC. The systematic review was used to identify and analyze six major knowledge themes (e.g., environmental, economic, social, decision-making, optimization, and industry management) and 21 knowledge topics for SROSC. We proposed possible future research directions based on the resulting structured body of knowledge. This research contributes to the body of knowledge by visualizing and analyzing the state-of-the-art of SROSC, as well as identifying the future research directions in this area to improve architectural, engineering, and construction practices.